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ROCK inhibitor reduces Myc-induced apoptosis and mediates immortalization of human keratinocytes
The Myc/Max/Mad network plays a critical role in cell proliferation, differentiation and apoptosis and c-Myc is overexpressed in many cancers, including HPV-positive cervical cancer cell lines. Despite the tolerance of cervical cancer keratinocytes to high Myc expression, we found that the solitary...
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| Published in: | Oncotarget |
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| Main Authors: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Impact Journals LLC
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5341834/ https://ncbi.nlm.nih.gov/pubmed/27556514 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11458 |
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