Limits and potential of targeted sequencing analysis of liquid biopsy in patients with lung and colon carcinoma

The circulating free tumor DNA (ctDNA) represents an alternative, minimally invasive source of tumor DNA for molecular profiling. Targeted sequencing with next generation sequencing (NGS) can assess hundred mutations starting from a low DNA input. We performed NGS analysis of ctDNA from 44 patients...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Rachiglio, Anna Maria, Abate, Riziero Esposito, Sacco, Alessandra, Pasquale, Raffaella, Fenizia, Francesca, Lambiase, Matilde, Morabito, Alessandro, Montanino, Agnese, Rocco, Gaetano, Romano, Carmen, Nappi, Anna, Iaffaioli, Rosario Vincenzo, Tatangelo, Fabiana, Botti, Gerardo, Ciardiello, Fortunato, Maiello, Monica R., De Luca, Antonella, Normanno, Nicola
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5341823/
https://ncbi.nlm.nih.gov/pubmed/27448974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10704
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