BRAF V600E mutation in metastatic colorectal cancer: Methods of detection and correlation with clinical and pathologic features

The screening for BRAF V600E mutation is employed in clinical practice for its prognostic and potentially predictive role in patients with metastatic colorectal carcinoma (mCRC). Little information is available on the sensitivity and specificity of the testing methods to detect this mutation in CRC....

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Bibliographic Details
Published in:Cancer Biol Ther
Main Authors: Roma, Cristin, Rachiglio, Anna Maria, Pasquale, Raffaella, Fenizia, Francesca, Iannaccone, Alessia, Tatangelo, Fabiana, Antinolfi, Giuseppe, Parrella, Paola, Graziano, Paolo, Sabatino, Lina, Colantuoni, Vittorio, Botti, Gerardo, Maiello, Evaristo, Normanno, Nicola
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2016
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004691/
https://ncbi.nlm.nih.gov/pubmed/27261210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2016.1195048
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