MYCN and HDAC5 transcriptionally repress CD9 to trigger invasion and metastasis in neuroblastoma

The systemic and resistant nature of metastatic neuroblastoma renders it largely incurable with current multimodal treatment. Clinical progression stems mainly from the increasing burden of metastatic colonization. Therapeutically inhibiting the migration-invasion-metastasis cascade would be of grea...

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Publicado en:Oncotarget
Autores principales: Fabian, Johannes, Opitz, Desirée, Althoff, Kristina, Lodrini, Marco, Hero, Barbara, Volland, Ruth, Beckers, Anneleen, de Preter, Katleen, Decock, Anneleen, Patil, Nitin, Abba, Mohammed, Kopp-Schneider, Annette, Astrahantseff, Kathy, Wünschel, Jasmin, Pfeil, Sebastian, Ercu, Maria, Künkele, Annette, Hu, Jamie, Thole, Theresa, Schweizer, Leonille, Mechtersheimer, Gunhild, Carter, Daniel, Cheung, Belamy B., Popanda, Odilia, von Deimling, Andreas, Koster, Jan, Versteeg, Rogier, Schwab, Manfred, Marshall, Glenn M., Speleman, Frank, Erb, Ulrike, Zoeller, Margot, Allgayer, Heike, Simon, Thorsten, Fischer, Matthias, Kulozik, Andreas E., Eggert, Angelika, Witt, Olaf, Schulte, Johannes H., Deubzer, Hedwig E.
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2016
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Priority Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5341807/
https://ncbi.nlm.nih.gov/pubmed/27572323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11662
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