MYCN and HDAC5 transcriptionally repress CD9 to trigger invasion and metastasis in neuroblastoma

The systemic and resistant nature of metastatic neuroblastoma renders it largely incurable with current multimodal treatment. Clinical progression stems mainly from the increasing burden of metastatic colonization. Therapeutically inhibiting the migration-invasion-metastasis cascade would be of grea...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Fabian, Johannes, Opitz, Desirée, Althoff, Kristina, Lodrini, Marco, Hero, Barbara, Volland, Ruth, Beckers, Anneleen, de Preter, Katleen, Decock, Anneleen, Patil, Nitin, Abba, Mohammed, Kopp-Schneider, Annette, Astrahantseff, Kathy, Wünschel, Jasmin, Pfeil, Sebastian, Ercu, Maria, Künkele, Annette, Hu, Jamie, Thole, Theresa, Schweizer, Leonille, Mechtersheimer, Gunhild, Carter, Daniel, Cheung, Belamy B., Popanda, Odilia, von Deimling, Andreas, Koster, Jan, Versteeg, Rogier, Schwab, Manfred, Marshall, Glenn M., Speleman, Frank, Erb, Ulrike, Zoeller, Margot, Allgayer, Heike, Simon, Thorsten, Fischer, Matthias, Kulozik, Andreas E., Eggert, Angelika, Witt, Olaf, Schulte, Johannes H., Deubzer, Hedwig E.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Priority Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5341807/
https://ncbi.nlm.nih.gov/pubmed/27572323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11662
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