Methods of defining the non-inferiority margin in randomized, double-blind controlled trials: a systematic review

BACKGROUND: There is no consensus on the preferred method for defining the non-inferiority margin in non-inferiority trials, and previous studies showed that the rationale for its choice is often not reported. This study investigated how the non-inferiority margin is defined in the published literat...

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Detalhes bibliográficos
Publicado no:Trials
Main Authors: Althunian, Turki A., de Boer, Anthonius, Klungel, Olaf H., Insani, Widya N., Groenwold, Rolf H. H.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5341347/
https://ncbi.nlm.nih.gov/pubmed/28270184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-017-1859-x
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