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Room for Improvement in Conducting and Reporting Non-Inferiority Randomized Controlled Trials on Drugs: A Systematic Review

BACKGROUND: A non-inferiority (NI) trial is intended to show that the effect of a new treatment is not worse than the comparator. We conducted a review to identify how NI trials were conducted and reported, and whether the standard requirements from the guidelines were followed. METHODOLOGY AND PRIN...

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Detalhes bibliográficos
Main Authors: Wangge, Grace, Klungel, Olaf H., Roes, Kit C. B., de Boer, Anthonius, Hoes, Arno W., Knol, Mirjam J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965079/
https://ncbi.nlm.nih.gov/pubmed/21048948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013550
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