Activity screening of environmental metagenomic libraries reveals novel carboxylesterase families

Metagenomics has made accessible an enormous reserve of global biochemical diversity. To tap into this vast resource of novel enzymes, we have screened over one million clones from metagenome DNA libraries derived from sixteen different environments for carboxylesterase activity and identified 714 p...

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Publicado en:Sci Rep
Main Authors: Popovic, Ana, Hai, Tran, Tchigvintsev, Anatoly, Hajighasemi, Mahbod, Nocek, Boguslaw, Khusnutdinova, Anna N., Brown, Greg, Glinos, Julia, Flick, Robert, Skarina, Tatiana, Chernikova, Tatyana N., Yim, Veronica, Brüls, Thomas, Paslier, Denis Le, Yakimov, Michail M., Joachimiak, Andrzej, Ferrer, Manuel, Golyshina, Olga V., Savchenko, Alexei, Golyshin, Peter N., Yakunin, Alexander F.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5341072/
https://ncbi.nlm.nih.gov/pubmed/28272521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44103
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