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UMI-tools: modeling sequencing errors in Unique Molecular Identifiers to improve quantification accuracy

Unique Molecular Identifiers (UMIs) are random oligonucleotide barcodes that are increasingly used in high-throughput sequencing experiments. Through a UMI, identical copies arising from distinct molecules can be distinguished from those arising through PCR amplification of the same molecule. Howeve...

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Detalhes bibliográficos
Publicado no:Genome Res
Main Authors: Smith, Tom, Heger, Andreas, Sudbery, Ian
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5340976/
https://ncbi.nlm.nih.gov/pubmed/28100584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.209601.116
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