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Hierarchical clustering can identify B cell clones with high confidence in Ig repertoire sequencing data()
Adaptive immunity is driven by the expansion, somatic hypermutation, and selection of B cell clones. Each clone is the progeny of a single B cell responding to antigen, with diversified Ig receptors. These receptors can now be profiled at large-scale by next-generation sequencing. Such data provide...
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| Udgivet i: | J Immunol |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5340603/ https://ncbi.nlm.nih.gov/pubmed/28179494 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601850 |
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