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Axon Termination, Pruning, and Synaptogenesis in the Giant Fiber System of Drosophila melanogaster Is Promoted by Highwire

The ubiquitin ligase Highwire has a conserved role in synapse formation. Here, we show that Highwire coordinates several facets of central synapse formation in the Drosophila melanogaster giant fiber system, including axon termination, axon pruning, and synaptic function. Despite the similarities to...

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Publicado en:Genetics
Autores principales: Borgen, Melissa, Rowland, Kimberly, Boerner, Jana, Lloyd, Brandon, Khan, Aruna, Murphey, Rodney
Formato: Artigo
Lenguaje:Inglês
Publicado: Genetics Society of America 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5340335/
https://ncbi.nlm.nih.gov/pubmed/28100586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.116.197343
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