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Axon Termination, Pruning, and Synaptogenesis in the Giant Fiber System of Drosophila melanogaster Is Promoted by Highwire

The ubiquitin ligase Highwire has a conserved role in synapse formation. Here, we show that Highwire coordinates several facets of central synapse formation in the Drosophila melanogaster giant fiber system, including axon termination, axon pruning, and synaptic function. Despite the similarities to...

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Detalhes bibliográficos
Publicado no:Genetics
Main Authors: Borgen, Melissa, Rowland, Kimberly, Boerner, Jana, Lloyd, Brandon, Khan, Aruna, Murphey, Rodney
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5340335/
https://ncbi.nlm.nih.gov/pubmed/28100586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.116.197343
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