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Axon Termination, Pruning, and Synaptogenesis in the Giant Fiber System of Drosophila melanogaster Is Promoted by Highwire

The ubiquitin ligase Highwire has a conserved role in synapse formation. Here, we show that Highwire coordinates several facets of central synapse formation in the Drosophila melanogaster giant fiber system, including axon termination, axon pruning, and synaptic function. Despite the similarities to...

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Библиографические подробности
Опубликовано в: :Genetics
Главные авторы: Borgen, Melissa, Rowland, Kimberly, Boerner, Jana, Lloyd, Brandon, Khan, Aruna, Murphey, Rodney
Формат: Artigo
Язык:Inglês
Опубликовано: Genetics Society of America 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5340335/
https://ncbi.nlm.nih.gov/pubmed/28100586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.116.197343
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