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Axon Termination, Pruning, and Synaptogenesis in the Giant Fiber System of Drosophila melanogaster Is Promoted by Highwire

The ubiquitin ligase Highwire has a conserved role in synapse formation. Here, we show that Highwire coordinates several facets of central synapse formation in the Drosophila melanogaster giant fiber system, including axon termination, axon pruning, and synaptic function. Despite the similarities to...

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Bibliografiset tiedot
Julkaisussa:Genetics
Päätekijät: Borgen, Melissa, Rowland, Kimberly, Boerner, Jana, Lloyd, Brandon, Khan, Aruna, Murphey, Rodney
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Genetics Society of America 2017
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5340335/
https://ncbi.nlm.nih.gov/pubmed/28100586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.116.197343
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