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AXL modulates extracellular matrix protein expression and is essential for invasion and metastasis in endometrial cancer

The receptor tyrosine kinase AXL promotes migration, invasion, and metastasis. Here, we evaluated the role of AXL in endometrial cancer. High immunohistochemical expression of AXL was found in 76% (63/83) of advanced-stage, and 77% (82/107) of high-grade specimens and correlated with worse survival...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Divine, Laura M., Nguyen, Mai R., Meller, Eric, Desai, Riva A., Arif, Batool, Rankin, Erinn B., Bligard, Katherine H., Meyerson, Cherise, Hagemann, Ian S., Massad, Maria, Thaker, Premal H., Hagemann, Andrea R., McCourt, Carolyn K., Powell, Matt A., Mutch, David G., Fuh, Katherine C.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5340229/
https://ncbi.nlm.nih.gov/pubmed/27764792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12637
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