Hedgehog and TGFβ signaling converge on Gli2 to control bony invasion and bone destruction in oral squamous cell carcinoma

Oral Squamous Cell Carcinoma (OSCC) is the sixth most common cancer worldwide. OSCC invasion into the lymph nodes and mandible correlates with increased rates of recurrence and lower overall survival. Tumors that infiltrate mandibular bone proliferate rapidly and induce bone destruction. While survi...

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Publicado en:Oncotarget
Autores principales: Cannonier, Shellese A., Gonzales, Cara B., Ely, Kim, Guelcher, Scott A., Sterling, Julie A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5340177/
https://ncbi.nlm.nih.gov/pubmed/27738315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12584
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