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Hedgehog and TGFβ signaling converge on Gli2 to control bony invasion and bone destruction in oral squamous cell carcinoma

Oral Squamous Cell Carcinoma (OSCC) is the sixth most common cancer worldwide. OSCC invasion into the lymph nodes and mandible correlates with increased rates of recurrence and lower overall survival. Tumors that infiltrate mandibular bone proliferate rapidly and induce bone destruction. While survi...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Cannonier, Shellese A., Gonzales, Cara B., Ely, Kim, Guelcher, Scott A., Sterling, Julie A.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5340177/
https://ncbi.nlm.nih.gov/pubmed/27738315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12584
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