Specific CpG hyper-methylation leads to Ankrd26 gene down-regulation in white adipose tissue of a mouse model of diet-induced obesity

Epigenetic modifications alter transcriptional activity and contribute to the effects of environment on the individual risk of obesity and Type 2 Diabetes (T2D). Here, we have estimated the in vivo effect of a fat-enriched diet (HFD) on the expression and the epigenetic regulation of the Ankyrin rep...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Raciti, Gregory A., Spinelli, Rosa, Desiderio, Antonella, Longo, Michele, Parrillo, Luca, Nigro, Cecilia, D’Esposito, Vittoria, Mirra, Paola, Fiory, Francesca, Pilone, Vincenzo, Forestieri, Pietro, Formisano, Pietro, Pastan, Ira, Miele, Claudia, Beguinot, Francesco
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2017
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5339897/
https://ncbi.nlm.nih.gov/pubmed/28266632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43526
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