Specific CpG hyper-methylation leads to Ankrd26 gene down-regulation in white adipose tissue of a mouse model of diet-induced obesity

Epigenetic modifications alter transcriptional activity and contribute to the effects of environment on the individual risk of obesity and Type 2 Diabetes (T2D). Here, we have estimated the in vivo effect of a fat-enriched diet (HFD) on the expression and the epigenetic regulation of the Ankyrin rep...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Raciti, Gregory A., Spinelli, Rosa, Desiderio, Antonella, Longo, Michele, Parrillo, Luca, Nigro, Cecilia, D’Esposito, Vittoria, Mirra, Paola, Fiory, Francesca, Pilone, Vincenzo, Forestieri, Pietro, Formisano, Pietro, Pastan, Ira, Miele, Claudia, Beguinot, Francesco
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5339897/
https://ncbi.nlm.nih.gov/pubmed/28266632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43526
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