WSB1 overcomes oncogene-induced senescence by targeting ATM for degradation

Oncogene-induced senescence (OIS) or apoptosis through the DNA-damage response is an important barrier of tumorigenesis. Overcoming this barrier leads to abnormal cell proliferation, genomic instability, and cellular transformation, and finally allows cancers to develop. However, it remains unclear...

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Bibliografski detalji
Izdano u:Cell Res
Glavni autori: Kim, Jung Jin, Lee, Seung Baek, Yi, Sang-Yeop, Han, Sang-Ah, Kim, Sun-Hyun, Lee, Jong-Min, Tong, Seo-Yun, Yin, Ping, Gao, Bowen, Zhang, Jun, Lou, Zhenkun
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2017
Teme:
Original Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5339850/
https://ncbi.nlm.nih.gov/pubmed/27958289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2016.148
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