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Single-molecule studies reveal reciprocating of WRN helicase core along ssDNA during DNA unwinding
Werner syndrome is caused by mutations in the WRN gene encoding WRN helicase. A knowledge of WRN helicase’s DNA unwinding mechanism in vitro is helpful for predicting its behaviors in vivo, and then understanding their biological functions. In the present study, for deeply understanding the DNA unwi...
Shranjeno v:
| izdano v: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2017
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5339710/ https://ncbi.nlm.nih.gov/pubmed/28266653 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43954 |
| Oznake: |
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