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OGG1-DNA interactions facilitate NF-κB binding to DNA targets

DNA repair protein counteracting oxidative promoter lesions may modulate gene expression. Oxidative DNA bases modified by reactive oxygen species (ROS), primarily as 7, 8-dihydro-8-oxo-2′-deoxyguanosine (8-oxoG), which is repaired by 8-oxoguanine DNA glycosylase1 (OGG1) during base excision repair (...

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書目詳細資料
發表在:Sci Rep
Main Authors: Pan, Lang, Hao, Wenjing, Zheng, Xu, Zeng, Xianlu, Ahmed Abbasi, Adeel, Boldogh, Istvan, Ba, Xueqing
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5339705/
https://ncbi.nlm.nih.gov/pubmed/28266569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43297
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