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OGG1-DNA interactions facilitate NF-κB binding to DNA targets
DNA repair protein counteracting oxidative promoter lesions may modulate gene expression. Oxidative DNA bases modified by reactive oxygen species (ROS), primarily as 7, 8-dihydro-8-oxo-2′-deoxyguanosine (8-oxoG), which is repaired by 8-oxoguanine DNA glycosylase1 (OGG1) during base excision repair (...
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| 發表在: | Sci Rep |
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| Main Authors: | , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5339705/ https://ncbi.nlm.nih.gov/pubmed/28266569 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43297 |
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