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Gestational diabetes leads to down-regulation of CDK4-pRB-E2F1 pathway genes in pancreatic islets of rat offspring

OBJECTIVE(S): The link between a hyperglycemic intrauterine environment and the development of diabetes later in life has been observed in offspring exposed to gestational diabetes mellitus (GDM), but the underlying mechanisms for this phenomenon are still not clear. Reduced β-cells mass is a determ...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Iran J Basic Med Sci
Egile Nagusiak: Nazari, Zahra, Nabiuni, Mohammad, Saeidi, Mohsen, Golalipour, Mohammad Jafar
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Mashhad University of Medical Sciences 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5339655/
https://ncbi.nlm.nih.gov/pubmed/28293391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22038/ijbms.2017.8240
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