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Avian and Human Seasonal Influenza Hemagglutinin Proteins Elicit CD4 T Cell Responses That Are Comparable in Epitope Abundance and Diversity

Avian influenza viruses remain a significant concern due to their pandemic potential. Vaccine trials have suggested that humans respond poorly to avian influenza vaccines relative to seasonal vaccines. It is important to understand, first, if there is a general deficiency in the ability of avian hem...

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Pubblicato in:Clin Vaccine Immunol
Autori principali: DiPiazza, Anthony, Richards, Katherine, Poulton, Nicholas, Sant, Andrea J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5339641/
https://ncbi.nlm.nih.gov/pubmed/28100497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00548-16
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