Diverse Epitope Specificity, Immunodominance Hierarchy, and Functional Avidity of Effector CD4 T Cells Established During Priming Is Maintained in Lung After Influenza A Virus Infection

One of the major contributions to protective immunity to influenza viruses that is provided by virus-specific CD4 T cells is delivery of effector function to the infected lung. However, there is little known about the selection and breadth of viral epitope-specific CD4 T cells that home to the lung...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Richards, Katherine A., DiPiazza, Anthony T., Rattan, Ajitanuj, Knowlden, Zackery A. G., Yang, Hongmei, Sant, Andrea J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5897437/
https://ncbi.nlm.nih.gov/pubmed/29681900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00655
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