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Increased RhoA Activity Predicts Worse Overall Survival in Patients Undergoing Surgical Resection for Lauren Diffuse-Type Gastric Adenocarcinoma

BACKGROUND: Several studies have reported a high rate of RHOA mutations in the Lauren diffuse-type gastric adenocarcinoma (GA) but not in intestinal-type GA. The aim of this study was to determine if RhoA activity is prognostic for overall survival (OS) in patients with resectable GA. METHODS: Retro...

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Detalhes bibliográficos
Publicado no:Ann Surg Oncol
Main Authors: Chang, Kevin K., Cho, Soo-Jeong, Yoon, Changhwan, Lee, Jun Ho, Park, Do Joong, Yoon, Sam S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5339626/
https://ncbi.nlm.nih.gov/pubmed/27364501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1245/s10434-016-5357-2
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