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RhoA Mutations Identified in Diffuse Gastric Cancer

The diffuse-type histologic variant of gastric cancer is characterized by highly invasive growth patterns and lack of cellular cohesion. Two recent studies have identified highly recurrent mutations of the gene encoding the small GTPase RhoA and suggest that RhoA activity may have a tumor suppressiv...

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Detalhes bibliográficos
Main Authors: Zhou, Jin, Hayakawa, Yoku, Wang, Timothy C., Bass, Adam J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4206186/
https://ncbi.nlm.nih.gov/pubmed/25026207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2014.06.022
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