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Conserved Glycine Residues in the Fusion Peptide of the Paramyxovirus Fusion Protein Regulate Activation of the Native State

Hydrophobic fusion peptides (FPs) are the most highly conserved regions of class I viral fusion-mediating glycoproteins (vFGPs). FPs often contain conserved glycine residues thought to be critical for forming structures that destabilize target membranes. Unexpectedly, a mutation of glycine residues...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Russell, Charles J., Jardetzky, Theodore S., Lamb, Robert A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC533953/
https://ncbi.nlm.nih.gov/pubmed/15564482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.24.13727-13742.2004
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