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Spring-Loaded Heptad Repeat Residues Regulate the Expression and Activation of Paramyxovirus Fusion Protein

During viral entry, the paramyxovirus fusion (F) protein fuses the viral envelope to a cellular membrane. Similar to other class I viral fusion glycoproteins, the F protein has two heptad repeat regions (HRA and HRB) that are important in membrane fusion and can be targeted by antiviral inhibitors....

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Detalhes bibliográficos
Main Authors: Luque, Laura E., Russell, Charles J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866055/
https://ncbi.nlm.nih.gov/pubmed/17251293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02464-06
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