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Bimolecular Complementation of Paramyxovirus Fusion and Hemagglutinin-Neuraminidase Proteins Enhances Fusion: Implications for the Mechanism of Fusion Triggering

For paramyxoviruses, entry requires a receptor-binding protein (hemagglutinin-neuraminidase [HN], H, or G) and a fusion protein (F). Like other class I viral fusion proteins, F is expressed as a prefusion metastable protein that undergoes a refolding event to induce fusion. HN binding to its recepto...

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Detalhes bibliográficos
Main Authors: Connolly, Sarah A., Leser, George P., Jardetzky, Theodore S., Lamb, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772755/
https://ncbi.nlm.nih.gov/pubmed/19710150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01191-09
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