Regulation of Paramyxovirus Fusion Activation: the Hemagglutinin-Neuraminidase Protein Stabilizes the Fusion Protein in a Pretriggered State

The hemagglutinin (HA)-neuraminidase protein (HN) of paramyxoviruses carries out three discrete activities, each of which affects the ability of HN to promote viral fusion and entry: receptor binding, receptor cleaving (neuraminidase), and triggering of the fusion protein. Binding of HN to its siali...

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Hlavní autoři: Porotto, Matteo, Salah, Zuhair W., Gui, Long, DeVito, Ilaria, Jurgens, Eric M., Lu, Hong, Yokoyama, Christine C., Palermo, Laura M., Lee, Kelly K., Moscona, Anne
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2012
Témata:
Virus-Cell Interactions
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497673/
https://ncbi.nlm.nih.gov/pubmed/22993149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01965-12
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