A Conserved Histidine in the ij Loop of the Semliki Forest Virus E1 Protein Plays an Important Role in Membrane Fusion

The enveloped alphavirus Semliki Forest virus (SFV) infects cells via a low pH-triggered membrane fusion reaction mediated by the E1 protein. E1 is a class II fusion protein that contains the hydrophobic fusion peptide loop and converts to a stable homotrimer during the fusion reaction. Intriguingly...

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Bibliographic Details
Main Authors: Chanel-Vos, Chantal, Kielian, Margaret
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2004
Subjects:
Structure and Assembly
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC533937/
https://ncbi.nlm.nih.gov/pubmed/15564465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.24.13543-13552.2004
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