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Role of Conserved Histidine Residues in the Low-pH Dependence of the Semliki Forest Virus Fusion Protein

A wide variety of enveloped viruses infects cells by taking advantage of the low pH in the endocytic pathway to trigger virus-membrane fusion. For alphaviruses such as Semliki Forest virus (SFV), acidic pH initiates a series of conformational changes in the heterodimeric virus envelope proteins E1 a...

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Detalles Bibliográficos
Main Authors: Qin, Zhao-ling, Zheng, Yan, Kielian, Margaret
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2009
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2668505/
https://ncbi.nlm.nih.gov/pubmed/19244325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02646-08
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