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Identification of a Specific Region in the E1 Fusion Protein Involved in Zinc Inhibition of Semliki Forest Virus Fusion
The enveloped alphaviruses infect cells via a low-pH-triggered membrane fusion reaction mediated by the viral transmembrane protein E1. During fusion, E1 inserts into the target membrane and refolds to a hairpin-like postfusion conformation in which domain III (DIII) and the juxtamembrane stem pack...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3302541/ https://ncbi.nlm.nih.gov/pubmed/22258261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.07115-11 |
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