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E1 Mutants Identify a Critical Region in the Trimer Interface of the Semliki Forest Virus Fusion Protein
The alphavirus Semliki Forest virus (SFV) uses a membrane fusion reaction to infect host cells. Fusion of the virus and cell membranes is triggered by low pH in the endosome and is mediated by the viral membrane protein E1. During fusion, E1 inserts into the target membrane, trimerizes, and refolds...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2772772/ https://ncbi.nlm.nih.gov/pubmed/19692469 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01147-09 |
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