Characterization of the Highly Prevalent Regulatory CD24(hi)CD38(hi) B-Cell Population in Human Cord Blood

The newborn’s immune system must transition from a sterile haploidentical uterus to the world full of antigens. Regulatory B-cells (Breg; broadly defined as CD19(+)CD24(hi)CD38(hi)) are tolerance promoters in the adult immune system. They can inhibit IFN-γ and IL-17 production by T-cells and are ess...

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Detalles Bibliográficos
Publicado en:Front Immunol
Main Authors: Esteve-Solé, Ana, Teixidó, Irene, Deyà-Martínez, Angela, Yagüe, Jordi, Plaza-Martín, Ana M., Juan, Manel, Alsina, Laia
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2017
Assuntos:
Immunology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5339297/
https://ncbi.nlm.nih.gov/pubmed/28326080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00201
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