Deficit of circulating CD19(+)CD24(hi)CD38(hi) regulatory B cells in severe aplastic anaemia

Immune aplastic anaemia (AA) is caused by cytotoxic T lymphocytes (CTLs) that destroy haematopoietic stem and progenitor cells. Enhanced type 1 T helper (Th1) responses and reduced regulatory T cells (Tregs) are involved in the immune pathophysiology. CD24(hi)CD38(hi) regulatory B cells (Bregs) supp...

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Publicado en:Br J Haematol
Autores principales: Zaimoku, Yoshitaka, Patel, Bhavisha A., Kajigaya, Sachiko, Feng, Xingmin, Alemu, Lemlem, Quinones Raffo, Diego, Groarke, Emma M., Young, Neal S.
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2020
Materias:
Red Cells and Iron
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7496711/
https://ncbi.nlm.nih.gov/pubmed/32311088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bjh.16651
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