Efficient Replication by Herpes Simplex Virus Type 1 Involves Activation of the IκB Kinase-IκB-p65 Pathway

Infection by herpes simplex virus type 1 (HSV-1) induces a persistent nuclear translocation of NFκB. To identify upstream effectors of NFκB and their effect on virus replication, we employed mouse embryo fibroblast (MEF)-derived cell lines with deletions of either IKK1 or IKK2, the catalytic subunit...

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Bibliografski detalji

Izdano u:	J Virol
Glavni autori:	Gregory, D., Hargett, D., Holmes, D., Money, E., Bachenheimer, S. L.
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 2004
Teme:	Virus-Cell Interactions
Online pristup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC533927/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15564469/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.24.13582-13590.2004
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