Efficient Replication by Herpes Simplex Virus Type 1 Involves Activation of the IκB Kinase-IκB-p65 Pathway

Infection by herpes simplex virus type 1 (HSV-1) induces a persistent nuclear translocation of NFκB. To identify upstream effectors of NFκB and their effect on virus replication, we employed mouse embryo fibroblast (MEF)-derived cell lines with deletions of either IKK1 or IKK2, the catalytic subunit...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Gregory, D., Hargett, D., Holmes, D., Money, E., Bachenheimer, S. L.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2004
Assuntos:	Virus-Cell Interactions
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC533927/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15564469/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.24.13582-13590.2004
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