Efficient Replication by Herpes Simplex Virus Type 1 Involves Activation of the IκB Kinase-IκB-p65 Pathway

Infection by herpes simplex virus type 1 (HSV-1) induces a persistent nuclear translocation of NFκB. To identify upstream effectors of NFκB and their effect on virus replication, we employed mouse embryo fibroblast (MEF)-derived cell lines with deletions of either IKK1 or IKK2, the catalytic subunit...

Whakaahuatanga katoa

Ngā taipitopito rārangi puna kōrero

I whakaputaina i:	J Virol
Ngā kaituhi matua:	Gregory, D., Hargett, D., Holmes, D., Money, E., Bachenheimer, S. L.
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	American Society for Microbiology (ASM) 2004
Ngā marau:	Virus-Cell Interactions
Urunga tuihono:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC533927/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15564469/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.24.13582-13590.2004
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!