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Role of the VP16-Binding Domain of vhs in Viral Growth, Host Shutoff Activity, and Pathogenesis

The virion host shutoff (vhs) protein of herpes simplex virus type 1 causes the degradation of host and viral mRNA immediately upon infection of permissive cells. vhs can interact with VP16 through a 20-amino-acid binding domain, and viruses containing a deletion of this VP16-binding domain of vhs (...

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Bibliografische gegevens
Hoofdauteurs: Strand, Stephanie S., Leib, David A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2004
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC533910/
https://ncbi.nlm.nih.gov/pubmed/15564467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.24.13562-13572.2004
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