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Role of the VP16-Binding Domain of vhs in Viral Growth, Host Shutoff Activity, and Pathogenesis
The virion host shutoff (vhs) protein of herpes simplex virus type 1 causes the degradation of host and viral mRNA immediately upon infection of permissive cells. vhs can interact with VP16 through a 20-amino-acid binding domain, and viruses containing a deletion of this VP16-binding domain of vhs (...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology
2004
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC533910/ https://ncbi.nlm.nih.gov/pubmed/15564467 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.24.13562-13572.2004 |
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