Identification of Residues in the Dengue Virus Type 2 NS2B Cofactor That Are Critical for NS3 Protease Activation

Proteolytic processing of the dengue virus polyprotein is mediated by host cell proteases and the virus-encoded NS2B-NS3 two-component protease. The NS3 protease represents an attractive target for the development of antiviral inhibitors. The three-dimensional structure of the NS3 protease domain ha...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Niyomrattanakit, Pornwaratt, Winoyanuwattikun, Pakorn, Chanprapaph, Santad, Angsuthanasombat, Chanan, Panyim, Sakol, Katzenmeier, Gerd
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC533897/
https://ncbi.nlm.nih.gov/pubmed/15564480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.24.13708-13716.2004
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados