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Entirely plasmid-based reverse genetics system for rotaviruses

Rotaviruses (RVs) are highly important pathogens that cause severe diarrhea among infants and young children worldwide. The understanding of the molecular mechanisms underlying RV replication and pathogenesis has been hampered by the lack of an entirely plasmid-based reverse genetics system. In this...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Kanai, Yuta, Komoto, Satoshi, Kawagishi, Takahiro, Nouda, Ryotaro, Nagasawa, Naoko, Onishi, Misa, Matsuura, Yoshiharu, Taniguchi, Koki, Kobayashi, Takeshi
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338561/
https://ncbi.nlm.nih.gov/pubmed/28137864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1618424114
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