Reverse Genetics Approach for Developing Rotavirus Vaccine Candidates Carrying VP4 and VP7 Genes Cloned from Clinical Isolates of Human Rotavirus

Species A rotaviruses (RVs) are a leading cause of severe acute gastroenteritis in infants and children younger than 5 years. Currently available RV vaccines were adapted from wild-type RV strains by serial passage of cultured cells or by reassortment between human and animal RV strains. These tradi...

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Detalles Bibliográficos
Publicado en:J Virol
Autores principales: Kanai, Yuta, Onishi, Misa, Kawagishi, Takahiro, Pannacha, Pimfhun, Nurdin, Jeffery A., Nouda, Ryotaro, Yamasaki, Moeko, Lusiany, Tina, Khamrin, Pattara, Okitsu, Shoko, Hayakawa, Satoshi, Ebina, Hirotaka, Ushijima, Hiroshi, Kobayashi, Takeshi
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2020
Materias:
Vaccines and Antiviral Agents
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7944460/
https://ncbi.nlm.nih.gov/pubmed/33087468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01374-20
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