A plasmid-based reverse genetics system for mammalian orthoreoviruses driven by a plasmid-encoded T7 RNA polymerase

Mammalian orthoreoviruses (reoviruses) have served as highly useful models for studies of virus replication and pathogenesis. The development of a plasmid-based reverse genetics system represented a major breakthrough in reovirus research. The current reverse genetics systems for reoviruses rely on...

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Bibliographic Details
Published in:J Virol Methods
Main Authors: Komoto, Satoshi, Kawagishi, Takahiro, Kobayashi, Takeshi, Ikizler, Mine, Iskarpatyoti, Jason, Dermody, Terence S., Taniguchi, Koki
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7067583/
https://ncbi.nlm.nih.gov/pubmed/24183920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jviromet.2013.10.023
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