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Kv1.1 channelopathy abolishes presynaptic spike width modulation by subthreshold somatic depolarization
Although action potentials propagate along axons in an all-or-none manner, subthreshold membrane potential fluctuations at the soma affect neurotransmitter release from synaptic boutons. An important mechanism underlying analog–digital modulation is depolarization-mediated inactivation of presynapti...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5338558/ https://ncbi.nlm.nih.gov/pubmed/28193892 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1608763114 |
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