Insights into immune system development and function from mouse T-cell repertoires

The ability of the adaptive immune system to respond to arbitrary pathogens stems from the broad diversity of immune cell surface receptors. This diversity originates in a stochastic DNA editing process (VDJ recombination) that acts on the surface receptor gene each time a new immune cell is created...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Sethna, Zachary, Elhanati, Yuval, Dudgeon, Crissy R., Callan, Curtis G., Levine, Arnold J., Mora, Thierry, Walczak, Aleksandra M.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2017
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338539/
https://ncbi.nlm.nih.gov/pubmed/28196891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1700241114
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