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LAG3 (CD223) as a Cancer Immunotherapy Target

Despite the impressive impact of CTLA4 and PD1-PDL1 targeted cancer immunotherapy, a large proportion of patients with many tumor types fail to respond. Consequently, the focus has shifted to targeting alternative inhibitory receptors (IRs) and suppressive mechanisms within the tumor microenvironmen...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Immunol Rev
Hauptverfasser: Andrews, Lawrence P., Marciscano, Ariel E., Drake, Charles G., Vignali, Dario A.A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338468/
https://ncbi.nlm.nih.gov/pubmed/28258692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12519
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