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LAG3 (CD223) as a Cancer Immunotherapy Target

Despite the impressive impact of CTLA4 and PD1-PDL1 targeted cancer immunotherapy, a large proportion of patients with many tumor types fail to respond. Consequently, the focus has shifted to targeting alternative inhibitory receptors (IRs) and suppressive mechanisms within the tumor microenvironmen...

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Detalhes bibliográficos
Publicado no:Immunol Rev
Main Authors: Andrews, Lawrence P., Marciscano, Ariel E., Drake, Charles G., Vignali, Dario A.A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338468/
https://ncbi.nlm.nih.gov/pubmed/28258692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12519
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