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Integrity of the human centromere DNA repeats is protected by CENP-A, CENP-C, and CENP-T
Centromeres are highly specialized chromatin domains that enable chromosome segregation and orchestrate faithful cell division. Human centromeres are composed of tandem arrays of α-satellite DNA, which spans up to several megabases. Little is known about the mechanisms that maintain integrity of the...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5338446/ https://ncbi.nlm.nih.gov/pubmed/28167779 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1615133114 |
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